Grade: A (Strong Scientific Evidence)
Therapy	Specific therapeutic Use(s)
Beta-glucan	Hyperlipidemia
Calcium	Cardiopulmonary resuscitation (CPR)
Niacin	High cholesterol (niacin)
Omega-3 fatty acids, fish oil, alpha-linolenic acid	Hypertriglyceridemia (fish oil / EPA plus DHA)
Policosanol	Hypercholesterolemia (high cholesterol)
Psyllium	High cholesterol
Red yeast rice	High cholesterol
Soy	High cholesterol
Grade: B (Good Scientific Evidence)
Therapy	Specific therapeutic Use(s)
Avocado	High cholesterol
Barley	Coronary heart disease (CHD)
Betaine anhydrous	Cardiovascular disease (in homocysteinuric patients)
Carob	Hypercholesterolemia (high cholesterol)
Chia	Cardiovascular disease prevention / atherosclerosis
Coleus	Cardiomyopathy
Cordyceps	Hyperlipidemia (high cholesterol)
Gamma oryzanol	Hyperlipidemia (high cholesterol)
Garlic	High cholesterol
Globe artichoke	Lipid-lowering
Grape seed	High cholesterol
L-Carnitine	Angina (chronic stable)
Niacin	Atherosclerosis (niacin)
Omega-3 fatty acids, fish oil, alpha-linolenic acid	Primary cardiovascular disease prevention (fish intake)
Pantethine	Hyperlipidemia (high cholesterol)
Policosanol	Coronary Heart Disease (CHD)
Sweet almond	High cholesterol (whole almonds)
Zinc	High cholesterol
Grade: C (Unclear or Conflicting Scientific Evidence)
Therapy	Specific therapeutic Use(s)
Alfalfa	Atherosclerosis (cholesterol plaques in heart arteries)
American hellebore	Cardiovascular and renal dysfunction
Aortic acid	Atherosclerosis
Arginine	Coronary artery disease / angina
Ashwagandha	High cholesterol
Astaxanthin	High cholesterol (LDL oxidation)
Astragalus	Coronary artery disease
Berberine	Hypercholesterolemia (high cholesterol)
Beta-glucan	Cardiovascular disease
Betaine anhydrous	Cholesterol levels
Bilberry	Atherosclerosis (hardening of the arteries), peripheral vascular disease
Black tea	Heart attack prevention / cardiovascular risk
Borage seed oil	Hyperlipidemia
Chamomile	Cardiovascular conditions
Chondroitin sulfate	Coronary artery disease (secondary prevention)
Chromium	Cardiovascular disease
Coenzyme Q10	Angina (chest pain from clogged heart arteries)
Copper	Cardiovascular disease prevention / atherosclerosis
Creatine	Heart muscle protection during heart surgery
Danshen	Cardiovascular disease / angina
DHEA	Cardiovascular disease
Dong quai	Angina pectoris / coronary artery disease
Elder	High cholesterol
Fenugreek	Hyperlipidemia
Flaxseed and flaxseed oil	Heart disease (flaxseed and flaxseed oil)
Folate	Vascular disease / hyperhomocysteinemia
Gamma oryzanol	Prevention of restenosis after coronary angioplasty (PTCA)
Garlic	Atherosclerosis (hardening of the arteries)
Ginseng	Coronary artery (heart) disease
Goldenseal	High cholesterol
Grapefruit	Heart disease
Green tea	Heart attack prevention
Guggul	Hypercholesterolemia
Gymnema	High cholesterol
Hawthorn	Coronary artery disease (angina)
Honey	Hypercholesterolemia (high cholesterol)
Horny goat weed	Atherosclerosis
Kudzu	Cardiovascular disease / angina
Lactobacillus acidophilus	High cholesterol
L-Carnitine	Hyperlipoproteinemia (high levels of lipoprotein and cholesterol in the blood)
Lemongrass	Hypercholesterolemia (high cholesterol)
Lutein	Atherosclerosis
Lycopene	Atherosclerosis (clogged arteries) and high cholesterol
Macrobiotic diet	Cholesterol
Milk thistle	High cholesterol
Nopal	Hyperlipidemia (high cholesterol)
Omega-3 fatty acids, fish oil, alpha-linolenic acid	Angina pectoris
Pantethine	Ischemic heart disease
Pantothenic acid	High cholesterol
Pomegranate	Atherosclerosis (hardening of the arteries)
Pycnogenol	High cholesterol
Quercetin	Cardiovascular disease
Red clover	Cardiovascular - blood flow
Red yeast rice	Coronary heart disease
Reishi mushroom	Coronary heart disease
Resveratrol	Cardiovascular disease
Rhubarb	Hypercholesterolemia (high cholesterol)
Safflower	Angina pectoris / coronary artery disease
Scotch broom	Cardiovascular conditions
Sea buckthorn	Cardiovascular disease
Selenium	Cardiomyopathy
Soy	Cardiovascular disease
Spirulina	High cholesterol
Squill	Coronary artery disease
Taurine	Hypercholesterolemia (high cholesterol)
Thiamin	Atherosclerosis (prevention in patients with acute hyperglycemia, impaired glucose tolerance (IGT), and diabetes mellitus)
Thymus extract	Cardiomyopathy
Tribulus	Coronary artery disease
Turmeric	High cholesterol
Vitamin B12	Angioplasty
Vitamin B6	Angioplasty
Vitamin C	Ischemic heart disease
Vitamin D	Hypertriglyceridemia
Vitamin E	Angina
White horehound	High cholesterol
Wild yam	High cholesterol
Yucca	Hypercholesterolemia
Grade: D (Fair Negative Scientific Evidence)
Therapy	Specific therapeutic Use(s)
Acacia	Hypercholesterolemia (high cholesterol)
Beta-carotene	Abdominal aortic aneurysm (AAA) prevention
Evening primrose oil	Cardiovascular health
Omega-3 fatty acids, fish oil, alpha-linolenic acid	Hypercholesterolemia
Vitamin C	Heart disease prevention
Vitamin E	Heart disease prevention
Traditional or Theoretical Uses which Lack Sufficient Evidence
Therapy	Specific therapeutic Use(s)
Abuta	Hypercholesterolemia (high cholesterol)
Acerola	Atherosclerosis (hardening of the arteries)
Aconite	Heart disease
Adrenal extract	Cholesterol
African wild potato	Coronary disease
Agrimony	Cardiotonic (restores heart strength)
Algin	Hyperlipidemia (high cholesterol)
Aloe	Heart disease prevention
Alpinia	Cardiovascular disease
American hellebore	Cardiac conditions
Anise	Heart disease
Antineoplastons	Cholesterol/triglyceride abnormalities
Aortic acid	Angina (chest pain)
Apple cider vinegar	High cholesterol
Arabinoxylan	Cardiovascular disease
Arginine	Cardiac syndrome X
Arnica	Angina pectoris (chest pain)
Ashwagandha	Cardiovascular disease
Astaxanthin	Atherosclerosis (prevention)
Astragalus	Angina
Avocado	Atherosclerosis
Bacopa	Cardiotonic
Bael fruit	Angina pectoris (chest pain)
Baikal skullcap	High cholesterol
Banaba	Hyperlipidemia (high cholesterol)
Barberry	Cardiovascular disease
Bee pollen	High cholesterol (hyperlipidemia)
Berberine	Cardiovascular disease
Beta-carotene	Angina pectoris
Beta-glucan	Atherosclerosis (hardening of the arteries)
Betaine anhydrous	Angina (chest pain)
Bilberry	Angina (chest pain)
Biotin	Hyperlipidemia
Bitter melon	High cholesterol
Black cohosh	Heart disease/palpitations
Black currant	Cardiovascular disease (heart disease)
Bloodroot	Heart disease
Blue flag	Angina
Boron	High cholesterol
Boswellia	Hyperlipidemia (high cholesterol)
Bromelain	Angina
Bupleurum	Angina (chest pain)
Butterbur	Cardiovascular conditions
Calamus	Hyperlipidemia (high cholesterol)
Calcium	Cardiac arrest
Calendula	Atherosclerosis (clogged arteries)
California jimson weed	Chest pain
Cardamom	Cardiac conditions
Cat's claw	Heart disease
Chia	Angina
Chicory	Hyperlipidemia (high cholesterol)
Chlorophyll	Atherosclerosis (hardening of the arteries)
Choline	Cardiovascular health
Chondroitin sulfate	Angina
Chromium	Atherosclerosis
Cinnamon	Chest pain
Clove	Atherosclerosis (hardening of the arteries)
Codonopsis	Myocardial injury
Coenzyme Q10	Atherosclerosis
Coleus	Angina (chest pain)
Comfrey	Angina (chest pain)
Copper	Hypercholesterolemia (high cholesterol)
Cordyceps	Atherosclerosis (hardening of the arteries)
Creatine	Hyperhomocysteinemia
Dandelion	Cardiovascular disorders
Danshen	Clogged arteries
Devil's claw	Atherosclerosis
Devil's club	Heart disease
DHEA	Heart attack
DMSO	High cholesterol
Dogwood	Coronary heart disease
Dong quai	Atherosclerosis
Elecampane	Angina pectoris (chest pain)
Emu oil	Atherosclerosis (hardening of the arteries)
Evening primrose oil	Atherosclerosis
Fenugreek	Atherosclerosis (hardening of the arteries)
Feverfew	Heart muscle injury
Fo-ti	Angina pectoris (chest pain)
Gamma oryzanol	Atherosclerosis (hardening of the arteries)
Germanium	Angina
Ginger	Atherosclerosis
Ginkgo	Angina
Ginseng	Atherosclerosis
Globe artichoke	Atherosclerosis (hardening of the arteries)
Goldenseal	Atherosclerosis (hardening of the arteries)
Grape seed	Arteriosclerosis
Green tea	Artherosclerosis
Gymnema	Cardiovascular disease
Hawthorn	Cardiac murmurs
Hibiscus	Atherosclerosis (hardening of the arteries)
Holy basil	Atherosclerosis (hardening of the arteries)
Hops	Atherosclerosis
Horny goat weed	Angina
Hyssop	Cardiovascular conditions
Iodine	Hyperlipidemia
Jiaogulan	Atherosclerosis (hardening of the arteries)
Katuka	Hyperlipidemia (high cholesterol)
Khella	Angina (chest pain)
Kiwi	Cardiovascular health
Lactobacillus acidophilus	Heart disease
Lemongrass	Cardiovascular health (cardiac rate)
Licorice	High cholesterol
Liver extract	Cardiovascular disease
Lotus	Cardiotonic (increases strength and tone of the heart)
Lutein	Cardiovascular disease
Lycopene	Heart disease
Macrobiotic diet	Heart disease
Maitake mushroom	High cholesterol
Mangosteen	Cardiotonic
Meadowsweet	Heart disease
Melatonin	Cardiac syndrome X
Milk thistle	Ischemic injury
Mistletoe	Arteriosclerosis
Modified citrus pectin	Atherosclerosis (hardening of the arteries)
MSM	Cardiovascular - blood flow
Muira puama	Atherosclerosis (hardening of the arteries)
Myrcia	Cardiotonic
Neem	Cardiovascular disease (heart disease)
Niacin	Coronary heart disease (CHD)
Noni	Atherosclerosis (hardened arteries)
Nopal	Cardiovascular health
Nux vomica	Cardiovascular disorders
Octacosanol	Atherosclerosis (hardening of the arteries)
Oleander	Cardiac abnormalities
Omega-3 fatty acids, fish oil, alpha-linolenic acid	Acute myocardial infarction (heart attack)
Onion	Atherosclerosis (hardening of the arteries)
Pantethine	Coronary disease
Pantothenic acid	Hypertriglyceridemia
Perilla	Arteriosclerosis (hardening of the arteries)
Perillyl alcohol	Cardiovascular disease
Policosanol	Iatrogenic lipodystrophy (defective metabolism)
PSK	Atherosclerosis
Psyllium	Atherosclerosis (hardening of the arteries)
Pycnogenol	Atherosclerosis
Quercetin	Atherosclerosis
Raspberry	Atherosclerosis
Red clover	Cardiovascular disease
Red yeast rice	Artherosclerosis
Rehmannia	Coronary heart disease (postmenopausal symptoms)
Reishi mushroom	Angina pectoris
Resveratrol	Atherosclerosis
Riboflavin	Atherosclerosis
Rosemary	Atherosclerosis (hardening of the arteries)
Rutin	Atherosclerosis (arterial insufficiency)
Saccharomyces boulardii	Hyperlipidemia (high cholesterol)
Salvia divinorum	Cardiovascular disease
SAMe	Heart disease
Scotch broom	Angina
Sea buckthorn	Angina (chest pain)
Seaweed, kelp, bladderwrack	Atherosclerosis
Selenium	Atherosclerosis
Shark cartilage	Atherosclerosis (clogged arteries)
Shiitake	Atherosclerosis
Soy	Atherosclerosis
Spirulina	Atherosclerosis
Squill	Cardiotonic
Stinging nettle	Angina pectoris (chest pain)
Sweet almond	Heart disease
Sweet basil	Cardiovascular risk reduction
Tamarind	Chest pain
Tangerine	Atherosclerosis (hardening of the arteries)
Taurine	Cardiac abnormalities (cardiac contractility)
Thymus extract	Angina (chest pain)
Tribulus	Angina pectoris (chest pain)
Turmeric	Heart damage from doxorubicin (Adriamycin®
Valerian	Angina
Vitamin A	Heart disease
Vitamin B6	High cholesterol
Vitamin C	Atherosclerosis (hardening of the arteries)
Vitamin E	Cardiomyopathy
Vitamin O	Atherosclerosis (hardening of the arteries)
Wild yam	Cardiovascular disease
Willow bark	Coronary artery disease prevention
Yellow dock	High cholesterol
Yerba santa	Hypercholesterolemia (high cholesterol)
Yew	Cardiovascular health
Yohimbe bark extract	Angina