Antineoplastons
Natural Standard evidence-based flashcard. Copyright © 2008 (www.naturalstandard.com). Commercial distribution prohibited. This flashcard is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions. 		Image
While some complementary and alternative techniques have been studied scientifically, high-quality data regarding safety, effectiveness, and mechanism of action are limited or controversial for most therapies. Whenever possible, it is recommended that practitioners be licensed by a recognized professional organization that adheres to clearly published standards. In addition, before starting a new technique or engaging a practitioner, it is recommended that patients speak with their primary healthcare provider(s). Potential benefits, risks (including financial costs), and alternatives should be carefully considered. The below monograph is designed to provide historical background and an overview of clinically-oriented research, and neither advocates for or against the use of a particular therapy.

Summary:
Antinioplastons are substances found in normal human blood and urine. In the late 1970s Dr. Stanislaw Burzynski found that they were not in the urine of cancer patients, and so researchers began studying antineoplastons as a possible treatment for cancer. The U.S. Food and Drug Administration (FDA) has not approved therapies involving antineoplastons, and it is not commonly used throughout the United States.

Uses
These uses have been tested in humans or animals. Safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider.
Grade*
Cancer C
Sickle cell anemia/thalassemia C
*Key to grades: A: Strong scientific evidence for this use; B: Good scientific evidence for this use; C: Unclear scientific evidence for this use; D: Fair scientific evidence against this use (it may not work); F: Strong scientific evidence against this use (it likely does not work).

Safety:
Avoid if allergic or hypersensitive to antineoplastons. Use cautiously with high medical or psychiatric risk, an active infection due to a possible decrease in white blood cells, high blood pressure, heart conditions, chronic obstructive pulmonary disease, liver disease/damage, kidney disease/damage. Avoid if pregnant or breastfeeding.

Possible side effects:
Drowsiness, headache, fatigue, mild dizziness/vertigo, and confusion, weakness, nausea, vomiting, upset stomach, abdominal pain, sore throat, fever, gas, chills, reduced blood albumin levels, liver function test abnormalities, low blood sugar levels, low potassium, palpitations, high blood pressure, water retention, chest pressure and irregular or fast heartbeat, joint swelling, muscle/joint pain, muscle contractions in the throat, finger rigidity, decreases in blood platelets/red blood cells/white blood cells, abnormal breathing, metabolic/electrolyte abnormalities, cerebral edema (brain swelling), dangerously low blood pressure, death.

Possible interactions:
Chemotherapy drugs (cancer drugs), drugs that decrease potassium levels in the blood, drugs that effect blood sugar levels, phenyl acetate, and herbs or supplements with similar effects.

Dosing:

Adults (18 years and older):
Please check with your medical oncologist before taking herbs and supplements if you have cancer.

Children (18 years and younger):
Please check with your medical oncologist before taking herbs and supplements if you have cancer.
Natural Standard Monograph (www.naturalstandard.com)
Copyright © 2008 Natural Standard Inc. Commercial distribution or reproduction prohibited.
The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.