Arabinoxylan
Natural Standard evidence-based flashcard. Copyright © 2008 (www.naturalstandard.com). Commercial distribution prohibited. This flashcard is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions. 		Image
While some complementary and alternative techniques have been studied scientifically, high-quality data regarding safety, effectiveness, and mechanism of action are limited or controversial for most therapies. Whenever possible, it is recommended that practitioners be licensed by a recognized professional organization that adheres to clearly published standards. In addition, before starting a new technique or engaging a practitioner, it is recommended that patients speak with their primary healthcare provider(s). Potential benefits, risks (including financial costs), and alternatives should be carefully considered. The below monograph is designed to provide historical background and an overview of clinically-oriented research, and neither advocates for or against the use of a particular therapy.

Summary:
Arabinoxylan, made from rice bran and mushroom extract, has been used to support individuals with low white blood cell counts caused by chemotherapy. It has also been used to support the immune system of those undergoing treatment for cancer/viral infections, including HIV infected patients. However, scientific evidence in humans is currently lacking.

Uses
These uses have been tested in humans or animals. Safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider.
Grade*
Cancer (various types) C
Diabetes (type 2) C
*Key to grades: A: Strong scientific evidence for this use; B: Good scientific evidence for this use; C: Unclear scientific evidence for this use; D: Fair scientific evidence against this use (it may not work); F: Strong scientific evidence against this use (it likely does not work).

Safety:
Use cautiously if elderly or with kidney dysfunction, due to potentially high calcium and phosphorus content. Use cautiously with diabetes. Avoid if pregnant or breastfeeding.
Users of MGN-3 (BioBranâ) should be aware of other constituents (cornstarch, dextrin, tricalcium phosphate, silicon dioxide). Patients with allergies to other constituents should not take MGN-3. It is not a proven treatment for cancer, diabetes or HIV.

Possible side effects:
There are no well-documented side effect reports available.

Possible interactions:
Calcium, cancer therapy, diabetes medications, drugs that alter immune system, phosphorus, herbs and supplements with similar effects.

Dosing:

Adults (18 years and older):
600mg-3g has been taken by mouth daily in divided doses.
The manufactured product MGN-3 (BioBranâ) contains 250mg arabinoxylan per 450mg tablet (in addition to cornstarch, dextrin, tricalcium phosphate, silicon dioxide).

Pediatric Dosing (age <18):
Not enough scientific evidence to recommend.
Natural Standard Monograph (www.naturalstandard.com)
Copyright © 2008 Natural Standard Inc. Commercial distribution or reproduction prohibited.
The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.