Asafoetida
Natural Standard evidence-based flashcard. Copyright © 2008 (www.naturalstandard.com). Commercial distribution prohibited. This flashcard is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.
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While some complementary and alternative techniques have been studied scientifically, high-quality data regarding safety, effectiveness, and mechanism of action are limited or controversial for most therapies. Whenever possible, it is recommended that practitioners be licensed by a recognized professional organization that adheres to clearly published standards. In addition, before starting a new technique or engaging a practitioner, it is recommended that patients speak with their primary healthcare provider(s). Potential benefits, risks (including financial costs), and alternatives should be carefully considered. The below monograph is designed to provide historical background and an overview of clinically-oriented research, and neither advocates for or against the use of a particular therapy.

Summary:
Asafoetida or asafetida (Ferula assafoetida) is a plant native to Iran (Middle East) that has a strong sulfurous smell. The sap of the stem and roots is dried and crushed to form an onion tasting powder, which is frequently used in Indian and Middle Eastern cuisine. One animal study found that asafoetida increased the calcium and zinc content in bone after exposure to radiation. However, there is currently insufficient evidence in humans to support the use of asafoetida for any indication.

Uses:
No available studies qualify for inclusion in the grading table.

Safety:
Avoid if allergic or hypersensitive to asafoetida (Ferula assafoetida), its constituents, or members of the Apiaceae family. Use cautiously if taking coagulation therapy. Avoid if pregnant or breastfeeding as asafoetida has traditionally been used as an abortifacient.

Possible side effects:
Cell poisoning, inhibition of the thymidine uptake into DNA.

Possible interactions:
Anti-cancer agents, anti-inflammatory agents, antispasmodic agents, bisphosphonates (non-hormonal drugs which are used to prevent and treat osteoporosis), blood pressure-altering agents, blood thinners, and herbs and supplements with similar effects.

Dosing:

Adults (18 years and older):
Not enough scientific data available.

Children (younger than 18 years):
Not enough scientific data available.
Natural Standard Monograph (www.naturalstandard.com)
Copyright © 2008 Natural Standard Inc. Commercial distribution or reproduction prohibited.

The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.